Internal block of human heart sodium channels by symmetrical tetra-alkylammoniums.
نویسندگان
چکیده
منابع مشابه
Internal block of human heart sodium channels by symmetrical tetra- alkylammoniums
The human heart Na channel (hH1) was expressed by transient transfection in tsA201 cells, and we examined the block of Na current by a series of symmetrical tetra-alkylammonium cations: tetramethylammonium (TMA), tetraethylammonium (TEA), tetrapropylammonium (TPrA), tetrabutylammonium (TBA), and tetrapentylammonium (TPeA). Internal TEA and TBA reduce single-channel current amplitudes while havi...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1994
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.104.3.507